Popular Medications That Can Make Your Muscles Weak – Health Digest



According to 2022 research published in the International Journal of Molecular Sciences, muscle-related symptoms have been estimated to affect anywhere between 10% and 15% of patients taking statin drugs. Although the exact cause of this relationship is not entirely clear, the calf muscles, thighs, buttocks, and back muscles are among the areas most often affected.

Certain drugs prescribed to treat heart arrhythmias, such as amiodarone, have also been linked with muscle weakness. The same is true for various antithyroid medications used to treat hyperthyroidism, like methimazole (via Medical News Today). Patients taking HIV antivirals like lamivudine or zidovudine may also experience reduced muscle strength. For patients diagnosed with cancer, muscle weakness may occur as a combined result of the disease and chemotherapy treatments. This is known as a condition called cachexia, which is characterized by skeletal muscle wasting (via the American Journal of Cancer Research).



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